- Welcome to MWF Forum.
Amidst pain, brotherhood
Recent posts
#1
OPEN TOPIC / Re: Robbies post
Last post by denny - February 29, 2024, 12:19:15 PMSorry robby.
Couldn't find modify.
Couldn't find modify.
#2
OPEN TOPIC / Robbies post
Last post by denny - February 11, 2024, 03:18:41 PMI fell asleep, and to add insult to injury,I fell off. 
#3
Medical News, New Research, Fibro Info / Med News Today -- Transitionin...
Last post by ronr - December 10, 2023, 06:52:31 PMDescent article on acute pain transition to chronic pain !!!
https://www.medicalnewstoday.com/articles/in-conversation-how-to-understand-chronic-pain?utm_source=ReadNext#Transitioning-from-acute-to-chronic-pain
An excerpt from about half way through this article:
We know that under a tissue [or nerve] injury of various sorts that we can activate signaling that normally is associated with what we call innate immunity. And one of the mediators of that is something called the toll-like receptor and it turns out that while those are normally there to recognize the presence of foreign bugs, for example, E. coli, those bugs have in their cell membrane, something called lipopolysaccharide, or LPS. We don't have that normally in our system, but it comes from bacteria," said Dr. Yaksh.
"You're born with it, you don't have to develop it. It's there all the time. What we've come to find out over the last years [t]hat there are many products that your body releases that will [a]ctivate those very same toll-like receptors," he added.
Toll-like receptors may prime the central immune system for heightened states of pain. In response to harmful stimuli, stressors, or tissue injury, especially in the microbiome or the gastrointestinal tract, the body starts to release products from inflammatory cells.
"When this happens, these products that are released from our own body can [a]ctivate these toll-like receptors, and there's [one] we call TLR4 [which] is present on inflammatory cells, and it's also present on sensory neurons," he explained.
Dr. Yaksh said that activating TLR4 itself doesn't cause as much pain, but that it sets the nervous system up to become more reactive.
Coupled with this priming, if there are other stressors present at the time—such as a bad diet or psychological distress, pointed out Dr. Guite— this can set off a whole cascade that can fuel this transition to chronic pain.
https://www.medicalnewstoday.com/articles/in-conversation-how-to-understand-chronic-pain?utm_source=ReadNext#Transitioning-from-acute-to-chronic-pain
An excerpt from about half way through this article:
We know that under a tissue [or nerve] injury of various sorts that we can activate signaling that normally is associated with what we call innate immunity. And one of the mediators of that is something called the toll-like receptor and it turns out that while those are normally there to recognize the presence of foreign bugs, for example, E. coli, those bugs have in their cell membrane, something called lipopolysaccharide, or LPS. We don't have that normally in our system, but it comes from bacteria," said Dr. Yaksh.
"You're born with it, you don't have to develop it. It's there all the time. What we've come to find out over the last years [t]hat there are many products that your body releases that will [a]ctivate those very same toll-like receptors," he added.
Toll-like receptors may prime the central immune system for heightened states of pain. In response to harmful stimuli, stressors, or tissue injury, especially in the microbiome or the gastrointestinal tract, the body starts to release products from inflammatory cells.
"When this happens, these products that are released from our own body can [a]ctivate these toll-like receptors, and there's [one] we call TLR4 [which] is present on inflammatory cells, and it's also present on sensory neurons," he explained.
Dr. Yaksh said that activating TLR4 itself doesn't cause as much pain, but that it sets the nervous system up to become more reactive.
Coupled with this priming, if there are other stressors present at the time—such as a bad diet or psychological distress, pointed out Dr. Guite— this can set off a whole cascade that can fuel this transition to chronic pain.
#4
VA Benefits or Curses / Re: won my new disablity claim
Last post by looneylane - November 11, 2023, 11:35:08 AMThat is so good that they have approved you!
#5
VA Benefits or Curses / Re: won my new disablity claim
Last post by ronr - November 10, 2023, 05:52:21 PM
#6
VA Benefits or Curses / Re: won my new disablity claim
Last post by foxgrove - November 10, 2023, 05:06:12 PMWahooooooooo!!! Right on Goldie!!! Long time in coming and well deserved. I'm so glad they finally went back and looked at it again. 
#7
VA Benefits or Curses / Re: won my new disablity claim
Last post by Robby - November 10, 2023, 08:02:28 AMThat is great, I am happy for you.
#8
VA Benefits or Curses / won my new disablity claim
Last post by augoldminer - November 09, 2023, 11:57:18 PMI finely did it.
After years i went from 10% to 60% VA disability.
Under the PACT ACT I now can prove I was exposed to Agent Orange.
I stopped at two new places added to the Agent Orange exposure list and applied and got approved.
After years i went from 10% to 60% VA disability.
Under the PACT ACT I now can prove I was exposed to Agent Orange.
I stopped at two new places added to the Agent Orange exposure list and applied and got approved.
#9
General Discussion / Re: Forum movements
Last post by Robby - October 31, 2023, 10:04:17 PMHey Stephen, here is a link to our server https://discord.gg/uNUYc8zK
#10
General Discussion / Re: Forum movements
Last post by ronr - October 30, 2023, 07:56:48 PMDid you like & follow the page menwithibro.com on facebook ??
I created another (private) facebook page also but can't even find it myself right now. That one is invite only so I'll have to try again on that one. Probly didn't save something.
Facebook has too many spies looking for what you say etc.
Discord shows that you have 2 accounts which is confusing for anyone to message you and must be confusing for you too.
Discord is more private without spies looking over your shoulder at what you say.
I have created a private channel within the discord channel when you get things squared away on your end with logging in.
I sent you a discord message Hollywood! Try to comment on that.
Went through ALL the settings on facebook and discord but there is no reason you cannot post on either site.
I created another (private) facebook page also but can't even find it myself right now. That one is invite only so I'll have to try again on that one. Probly didn't save something.
Facebook has too many spies looking for what you say etc.
Discord shows that you have 2 accounts which is confusing for anyone to message you and must be confusing for you too.
Discord is more private without spies looking over your shoulder at what you say.
I have created a private channel within the discord channel when you get things squared away on your end with logging in.
I sent you a discord message Hollywood! Try to comment on that.
Went through ALL the settings on facebook and discord but there is no reason you cannot post on either site.
SMF spam blocked by CleanTalk